The American Association of Pharmaceutical Scientists saw over 6500 attendees and 400 exhibitors attend their annual meeting and exposition at the Colorado Convention Center, Denver. This event started in back in 1986 and has grown to become the world’s largest meeting for pharmaceutical scientists.
The unseasonably warm weather spilled into the event, with plenty of hot topics being discussed in the seminars, at the digital posters and at the various exhibitor stands. To help capture the event, and to allow those who couldn’t attend to keep up with what’s going on, we shared live video news and updates from the show floor through AAPS Now.
Join Dr. Rowan Moore and Dr. Simon Cubbon as they guide you through this year’s show.
USP modernization, as well as a continued interest in large molecule content meant that there were three topics that clearly stood out from the crowd.
1. Extractables and Leachables/Impurities
Reducing risk and ensuring patient safety has been a topic of interest this year. With the advent of continuous processing and its recent backing by the FDA, the interest in implementation of single use bioprocessing technologies is clearly growing – and the resulting analysis of extractables & leachables has been the subject of a great number of presentations and posters.
Whilst we await the findings of the largest public research project to date, focussed on the migration of leachable impurities from bioprocess materials, check out this video interview with the leading researchers from NIBRT.
The results will be released in early 2017. You can register to be the first to receive them here.
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2. Pharmacopeial Updates
In case you missed it, the United States Pharmacopeia (USP) is modernizing! Many of the current methods rely upon classical wet chemistry procedures. These are often time consuming, labor-intensive, involve hazardous chemicals, require extensive analyst training, and may yield significant measurement errors.
This popular primer helps pharmaceutical manufacturers and contract labs understand and implement the new methodologies for the determination of elemental impurities.
3. Biopharmaceutical Characterization
With the huge potential that biotherapeutics can offer and their increasing complexity, there was a real increase in the number of talks and posters looking at biotherapeutic characterization compared to last year. We spoke to several CROs and CMOs about the challenges that they are facing when it comes to the intact, sub-unit and peptide mapping analyses that they need to perform.
We held a seminar talk about improved peptide mapping workflows, which is nicely summarized in this webinar series, as well as on our informative peptide mapping website where you can find scientific papers, infographics and much more!
Visit thermofisher.com/aaps where you can find and download all of the posters and presentations presented at AAPS 2016, the seminar videos and customer interviews will be available early 2017 so make sure you check back!
This post was co-authored by Dr. Simon Cubbon and Dr. Rowan Moore