One of the most important applications of ion chromatography (IC) is the determination of common inorganic anions in drinking water worldwide, and IC has been approved for compliance monitoring of common inorganic anions in U.S. drinking water since the mid-1980s, as described in U.S. EPA Method 300.0.1. Of course, numerous regulatory IC methods have been published in countries, such as Germany, France, Italy, and Japan and many standards organizations, such as the ISO, ASTM, and AWWA have validated IC methods for the determination of inorganic anions in drinking water.
Many anions in drinking water need to be regulated due to their toxic effects: for example, high levels of fluoride cause skeletal and dental fluorosis, and nitrite and nitrate can cause fatal methemoglobulinemia in infants.
In this blog post, we are pleased to feature our application starring our recently introduced high-pressure capillary ion chromatography (HPIC™) Reagent-Free system which can operate at pressures up to 5000 psi, which means that sample throughput can be increased by simply increasing the flow rate of analysis.
Application Brief, 141, Fast Determination of Inorganic Anions in Municipal Drinking Water Using Capillary Ion Chromatography, (downloadable PDF) describes the analysis of inorganic anions using an anion-exchange column (Thermo Scientific Dionex IonSwift MAX-100 capillary column) and suppressed conductivity detection where all analytes of interest are resolved within 8 min! The column is designed for the separation of small molecules including organic acids and inorganic anions using a hydroxide gradient delivered by an eluent generator.
You might also be interested in reading up on our newly released Capillary Fast IC columns that facilitate separations up to 4 times faster than conventional columns.
Let us know if you are using capillary IC in your analytical work in the comments box below. Also, don’t forget to add any questions or comments you might have regarding this application. Our experts will be pleased to answer your questions.