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Dr. Phil Widdowson

Company: Thermo Fisher Scientific, Inc.
Expertise: Pharma & Biopharma
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Phil commenced his role as part of the European Bio/Pharma CSC at Thermo Fisher Scientific in August 2018. Prior to starting this role, he was at Allergan Biologics, based in Speke, Liverpool, where he was a Senior Characterisation Scientist within the Analytical Development Team. In his eight years at Allergan, he was responsible for the physicochemical characterisation of biological therapeutics, primarily using liquid chromatography and mass spectrometry techniques. He is experienced in a wide range of analytical techniques for the physicochemical and biophysical characterisation of complex glycoproteins, however, his main area of expertise is in the application of glycoanalytical methods and workflows to protein therapeutics. He was responsible for building and driving Allergan’s capabilities in the glycoanalytical workspace and performed analyses at the intact protein, subunit, glycopeptide, released glycan and monosaccharide levels. In recent years he was responsible for assessing and implementing high-throughput glycan analysis, primarily to support in-house cell-line development strategies and automated glycan analytical approaches. Prior to working at Allergan, he gained his Ph.D. (“Biochemical and Biophysical Characterisation of Anopheles gambiae NADPH-Cytochrome P450 Reductase”) from the Centre for Structural Biology, at the University of Liverpool in 2010, where he used a range of biochemical and biophysical approaches – primarily Nuclear Magnetic Resonance (NMR) – to perform a direct comparison between human and mosquito P450 reductase proteins.

His experience in analytical characterisation, in particular glycan analysis, in the biopharmaceutical industry, has provided him with the tools and knowledge required to develop and implement pharmaceutical and biopharmaceutical analytical workflows. These workflows are driven by voice-of-customer (VOC) requirements, in addition to his technical experience, his eight years in the role of ‘customer’, has given him a direct perspective and insight into customer needs and the landscape of the industry.

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