chromatographer-2My June blog titled “Join the Mass Movement Towards Mass Spectrometry” discussed the benefits of mass spectrometry for ion chromatographers. That very month, Thermo Fisher Scientific launched the new Thermo Scientific™ ISQ™ EC single quadrupole mass spectrometer (MS) at HPLC 2017 in Prague. This mass spectrometer is designed with ease-of-use in mind for chromatographers who want to use MS to gain more insights from their samples.

For ion chromatographers, mass spectrometry enhances analyses with higher selectivity and, as a consequence, higher sensitivity and chromatographic peak confirmation. My last blog covered an example about resolving co-eluting peaks in an animal feed sample.

I want to share with you another example using a ground water sample analyzed with ion chromatography coupled to mass spectrometry. Four low-mass, inorganic cations are separated in six minutes. Since these cations have low mass-to-charge (m/z) ratios, they are particularly challenging to analyze. However, the ISQ EC single quadrupole MS excels at detecting low mass ions with a mass range of m/z 10–1250.

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To download more IC-MS methods using the ISQ EC single quadrupole MS, visit this resource page which also features an informative video on the system’s design.