My June blog titled “Join the Mass Movement Towards Mass Spectrometry” discussed the benefits of mass spectrometry for ion chromatographers. That very month, Thermo Fisher Scientific launched the new Thermo Scientific™ ISQ™ EC single quadrupole mass spectrometer (MS) at HPLC 2017 in Prague. This mass spectrometer is designed with ease-of-use in mind for chromatographers who want to use MS to gain more insights from their samples.
For ion chromatographers, mass spectrometry enhances analyses with higher selectivity and, as a consequence, higher sensitivity and chromatographic peak confirmation. My last blog covered an example about resolving co-eluting peaks in an animal feed sample.
I want to share with you another example using a ground water sample analyzed with ion chromatography coupled to mass spectrometry. Four low-mass, inorganic cations are separated in six minutes. Since these cations have low mass-to-charge (m/z) ratios, they are particularly challenging to analyze. However, the ISQ EC single quadrupole MS excels at detecting low mass ions with a mass range of m/z 10–1250.
Like what you are learning?
To download more IC-MS methods using the ISQ EC single quadrupole MS, visit this resource page which also features an informative video on the system’s design.