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Fast, High-Efficiency Separations on a 4 µm Ion Exchange Phase Using a High-Pressure Ion Chromatography System

Fast, High-Efficiency Separations on a 4 µm Ion Exchange Phase Using a High-Pressure Ion Chromatography System

Four µm columns separate analytes with greater efficiency, permitting the use of higher flow rates while maintaining resolution and reducing overall run time. Running any column at increased flow rates may cause a decrease in peak resolution. However, the superior chromatographic fidelity achieved using the new 4 µm columns, including the Dionex IonPac AS11-HC-4µm, Dionex IonPac AS18-4µm, and Dionex IonPac CS19- 4µm, minimizes such losses, to provide better separation of ions in complex matrices. Faster flow rates reduce run time and increases productivity when multiple samples are being analyzed, but back pressure is also increased, which is typically >3000 psi. To take advantage of the benefits of 4 µm columns, they should be combined with a highpressure instrument, such as the Dionex ICS-5000+ HPIC system, which can operate continuously at up to 5000 psi using eluent generation

Technique: Ion Chromatography Resource Type: Poster
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