As readers of this blog know by now that I typically don’t blog about products unless they are new and so when the announcement for this new biopharma UHPLC system (Thermo Scientific Dionex UltiMate 3000 Biocompatible Rapid Separation [BioRS] system) for a wide range of biopharmaceutical research and QA/QC analyses crossed my desk, I had to share it with our blog readers!
The system was developed to address the challenges of drug development workflows which can be demanding, require extensive data collection, organization, and analysis, accurate results, and fast separations. Corrosion-resistant materials in the complete system flow path reduce the risk of analyte interaction with internal surfaces and extend the lifetime of particular biocolumns, even under high salt or extreme pH conditions. Thus, the sytem provides reliability and robustness under the harsh solvent conditions applied in biochromatographic analyses.
The system design is optimized for many biomolecule applications include peptide mapping, monoclonal antibody charge variant analysis, glycan analysis, and nucleic acid analysis by allowing for easy method transfer between different stages of pharmaceutical product development and production.
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And, for those looking for a complete solution, we have dedicated bio UHPLC consumables, including our gold standard Thermo Scientific ProPac WCX protein analytical columns for QA/QC, UHPLC ion-exchange columns, and a wide range of mixed mode and HILIC columns.
One consumable I wanted to specially highlight was our virtually dead-volume-free UHPLC connector called the Thermo Scientific Dionex Viper Fingertight fitting system (image featured above) which provides the benefit of built-in zero dead volume by sealing at the tip of the tubing.
Don’t forget to check out posts on biopharmaceutical applications and research articles on this blog. Also, if you are looking for an application not blogged so far, do tell us in the Comments box below; our experts will be pleased to consider your request.