Fan Liu, PhD, Utrecht University, describes the use of crosslinking mass spectrometry and how it aids in the understanding of protein complexes. A recently developed novel search engine (XlinkX) for cross linking analysis, enabling analysts to search any database of unlimited database size, is also discussed, underscoring that crucial information of the structure and biology of many protein complexes is now within reach.
Test new limits of detection, characterization and quantitation with the latest Tribrid™ mass spectrometer. The Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ Mass Spectrometer is designed to expand performance in advanced proteomics, biopharma and metabolomics applications, including quantitation using isobaric tags, low level PTM analysis, data independent acquisition (DIA), and top down proteomics. The new instrument features enhanced sensitivity resulting in improved analyte detection, characterization and quantitation, enabling scientists to perform more comprehensive sample analyses faster and with better accuracy than ever before.Learn More Request Quote